Endocrine Abstracts

Introduction: Chronic catecholamine overproduction in pheochromocytoma may lead to a proinflammatory and hypermetabolic state characterized by increased resting energy expenditure and brown adipose tissue activation. Non-neoplastic hypercortisolaemia aka pseudo-Cushing syndrome (PCS) is a physiological overactivation of the hypothalamic–pituitary–adrenal axis by e.g. depression, eating disorders, extreme exercise, obesity, alcoholism, poorly controlled diabetes and c...

Introduction: Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy where alterations in the RET/PTC–RAS–BRAF signaling pathway and deregulation of microRNA (miRNA) expression are suggested to be major mechanism of pathogenesis. MicroRNAs are small non-coding RNA molecules that recognize specific sequences in 3′UTR of target gene and prevent from its translation. Our recent deep sequencing studies of thyroid tissue transcriptome revealed a put...